In The News
Platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis
Abstract Background This study aimed to evaluate the clinical efficacy of platelet-rich plasma (PRP) injection compared with hyaluronic acid (HA) injection for patients undergoing knee
Increasing Platelet Concentration in Platelet-Rich Plasma Inhibits Anterior Cruciate Ligament Cell Function in Three-Dimensional Culture
Abstract The anterior cruciate ligament (ACL) is a key stabiliz-er of the knee that is prone to injury, especially inyoung, active women. The annual incidence
Treatment of Tendon and Muscle Using Platelet-Rich Plasma
Abstract Musculoskeletal injuries and impairments result in over 100 million office visits in the United States per year. Tendons and muscle-related issues account for a
Treatment of Chronic Wounds with Autologous Platelet-Rich-Plasma
Abstract After treatment with platelet-rich plasma, 50% of the wounds had healed, 35.7% had reduced in size and 14.2% were unchanged in terms of area
Treatment of Chronic Elbow Tendinosis With Buffered Platelet-Rich Plasma
Abstract Treatment of patients with chronic elbow tendinosis with buffered platelet-rich plasma reduced pain significantly in this pilot investigation. Further evaluation of this novel treatment
Prevention of Disc Degeneration with Growth Factors
Abstract Clinically, a large number of patients have persistent low back pain attributable to intervertebral disc (IVD) degeneration. After the concept of biologically regenerating the
Platelet-Rich plasma- New clinical application- A pilot study for treatment of jumper’s knee
Abstract This study describes a simple, low-cost, minimally invasive way to apply PRP growth factors to chronic patellar tendinosis; 20 male athletes with a mean
Platelet-Rich Plasma- From Basic Science to Clinical Applications
Abstract Research into the biology of bone, ligament, and tendon healing has led to the development of a variety of products designed to help stimulate
Platelet Rich Plasma Injection Grafts for Musculoskeletal Injuries- A Review
Abstract In Europe and the United States, there is an increasing prevalence of the use of autologous blood products to facilitate healing in a variety
Platelet Rich Plasma in Rotator Cuff Repair
Abstract Despite clinical success rates over 85%, persistent anatomic defects after rotator cuff repair are common and depend on the size of the tear repaired.
Platelet Rich Plasma in Prolotherapy
Abstract Prolotherapy is a method of injection treatment designed to stimulate healing.’ Many different types of musculoskeletal injuries and pain lend themselves to prolotherapy treatment
Platelet Rich Plasma for Hamstring Tears
Abstract Platelet Rich Plasma (PRP) Injection Therapy is gaining popularity in musculoskeletal medicine, not only for its ease of use, but also its consistently good
Platelet Rich Plasma (PRP) Matrix Grafts
Abstract Platelet Rich Plasma (PRP) grafting techniques are now being utilized in musculoskeletal medicine with increasing frequency and effectiveness. Soft tissue injuries treated with PRP
Plasma Rich in Growth Factors to Treat an Articular Cartilage Avulsion- A Case Report
Abstract The application of an autologous plasma rich in growth factor~; is beneficial in restating connective tissues, as shown by clinical evidence in oral surgety
Biological Augmentation of Rotator Cuff Tendon Repair
Abstract A histologically normal insertion site does not regenerate following rotator cuff tendon-to-bone repair, which is likely due to abnormal or insufficient gene expression and/or
Autologous Fat Grafting as a Mesenchymal Stem Cell – Source and Living Bioscaffold in a Patellar Tendon Tear
Abstract The use of regenerative therapies in sports medicine has been increasing with the success of biologics such as plateletrich plasma (PRP). We present the
Diffusion and transport of extracellular vesicles
Abstract Cell-derived extracellular vesicles are important intercellular communicators involved in many biological processes and diseases, including cancer and cardiovascular diseases, but, thus far, how they
Manufacturing and characterization of extracellular vesicles from umbilical cord
Abstract Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) may deliver therapeutic effects that are comparable to their parental cells. MSC-EVs are promising agents
Extracellular Vesicles as a Potential Therapy for Neonatal Conditions
Abstract: Despite advances in intensive care, several neonatal conditions typically due to prematurity affect vital organs and are associated with high mortality and long-term morbidities.
Engineering Therapeutic Biological Nanoparticles that Truly Deliver
Abstract: Many aspects of intercellular communication are mediated through “sending” and “receiving” packets of information via the secretion and subsequent receptor-mediated detection of biomolecular species
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