Platelet-rich fibrin (PRF) is an alternative to Platelet Rich Plasma. PRF is an all-natural, autologous solution to treat many body areas. Properly harvested PRF has platelets, fibrin, and white blood cells, which help achieve wound healing, collagen production, and improved elasticity, along with many growth factors. PRF contains a very high concentration of white blood cells, fibrin, and a small number of regenerative cells found circulating in our bloodstream. PRF becomes a viscous gel after 15 to 20 minutes of being isolated and quickly after being injected into the body. The product is used as a stand-alone solution and scaffold for other injectables.
PRF is spun at a slower speed than PRP so that the layers of the blood do not separate as distinctly. This allows some white blood cells and regenerative cells to remain within the platelet layer collected for treatment. Thus, PRF has more healing factors than is typically seen in PRP. In addition, the lower spin speed causes less trauma to the individual cells of the blood, allowing more regenerative cells to remain in the final PRF product.