Exosomes are extracellular vesicles released from cells upon the fusion of a multivesicular body within the plasma membrane, liberating intraluminal vesicles into an extracellular environment. While they are made as intraluminal vesicles, the multivesicular body they reside in regulates whether these vesicles would become exosomes. They are associated with cellular communication that transfer molecules through body fluids to deliver nutrients and transmit disease states. Their cell of origin determines the proteins, lipids, nucleic acids, DNA and RNA species that act as passengers within an exosome. Exosomes regulate signaling, coagulation and waste management as intercellular communicators and carry distinctive functions depending on how their molecule composition disperses.
Exosomes have been explored as a means of treatment when applied to regenerative therapy as their ability to store molecular structures and tolerate treatment can createcells and alleviateinjuries.Since exosomes that are secreted from fibrocytes contain proteins and microRNA crucial in regulating collagen deposition and treating inflammation, theyhave been attributed to improving tissue health during wound therapy. Exosomes have been utilized in clinical applications for joint pain and bone fractures as they can invoke growth factors essential for musculoskeletal repair. Additionally, immune changes induced by exosomes can target inflammation and pain from joint conditions such as rheumatoid arthritis.
Exosomes can be tools for internal restoration by regulating cellular processes and restoring tissue health. Molecular structures transported through exosomes can target inflamed and damaged tissue, aiding in the recovery process and reducing pain and degradation in joints. Their ability to target tissue and ligament damage further assists and improves the body’s regenerative qualities. Utilizing exosomes for orthopedic therapy can protect joints and bones from the lasting effects of injuries, fractures and inflammation.
Learn more about the healing qualities of Exosomes
- Vesicles that transportproteins, lipids, nucleic acids, DNA, and RNA species throughout body fluids such as blood, urine, and cell cultures.
- Naturally occurring, contains high molecular weight of Hyaluronic Acid, contains Collagen types I & III which provide structural skin support.
- Contains growth factors NGF, SCF and VEGF for wound healing, growth and repair of skin; cartilage growth, repair and healing.
- Product rich in Collagen, Hyaluronic Acid, regenerative cell growth factors/proteins and complex amino acids.
- High volume of Chondroitin Sulfate.
- Regenerative Cell Factor – transmembrane soluble protein that aids in activating your own regenerative cells which aids in wound healing.
- Nerve Growth Factor- a polypeptide that in addition to its effects on nerve cells, it plays a role in tissue repair and that it can accelerate wound healing.
- Vascular Growth Factor – involved in signaling to restore oxygen supply to tissues.
- Regulate signaling, coagulation and waste management in the human body.
- Assist the body’s natural healing process by transporting cells and molecules essential for treating injuries.
- Can help repair wounds, bone fractures and inflamed or damaged tissue.
We are here to help your patients and your practice.
Through innovative technology, preparation & training.