Exosomes are extracellular vesicles released from cells upon the fusion of a multivesicular body within the plasma membrane, liberating intraluminal vesicles into an extracellular environment. While they are made as intraluminal vesicles, the multivesicular body they reside in regulates whether these vesicles would become exosomes. They are associated with cellular communication that transfers molecules through body fluids to deliver nutrients and transmit disease states. Their cell of origin determines the proteins, lipids, nucleic acids, DNA, and RNA species that act as passengers within an exosome.
Exosomes regulate signaling, coagulation, and waste management as intercellular communicators and carry distinctive functions depending on how their molecule composition disperses. Exosomes have been explored as a means of treatment when topically applied to the skin. Pre-clinical studies have shown exosomes,which are secreted from fibrocytes contain proteins and microRNA crucial in regulating collagen deposition and treating inflammation,have been attributed to improving tissue appearance, resilience, and elasticity.
Learn more about the qualities of Exosomes:
- Vesicles that transport proteins, lipids, nucleic acids, DNA, and RNA species throughout body fluids such as blood, urine, and cell cultures
- Naturally occurring, contains a high molecular weight of Hyaluronic Acid, contains Collagen types I & III which provide structural skin support
- Contains growth factors NGF, SCF, and VEGF for tissue rejuvenation
- Product rich in Collagen, Hyaluronic Acid, regenerative cell growth factors/proteins, and complex amino acids
- High volume of chondroitin sulfate
- Regenerative Cell Factor – transmembrane soluble protein that aids in activating your own cells
- Nerve Growth Factor – a polypeptide that in addition to its effects on nerve cells, it plays a role in tissue rejuvenation
- Vascular Growth Factor – involved in signaling to restore oxygen supply to tissues
- Regulate signaling, coagulation, and waste management in the human body
- Assist the body’s natural process by transporting cells and molecules
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