Anu RHEO+™ is a combination amniotic membrane matrix and Wharton’s Jelly that are minimally manipulated human tissue allografts, aseptically prepared for homologous use. Anu RHEO+™ aids in supplementing and replacing connective tissue that is damaged or inadequate. Amniotic fluid is a rich source of nutrients, cytokines, and the growth factors necessary for fetal development and maturation, and naturally protects the baby from hard blows or harsh temperatures. Wharton’s Jelly is a rich source of MSCs helping with the development of the fetus through its growth stages. With this in mind, RHEO+™ is a perfect match for synovial fluid in joints and its properties that are anti-scarring, anti-adhesion and anti-inflammatory make it essential for healing tissue damage.


Although corticoid steroid injections are a commonplace solution for inflammation and pain relief within the medical community, the properties in these injections lead to cartilage destruction by
disrupting the proliferative and remodeling process of healing. Meanwhile, the amniotic fluid in Anu RHEO™ provides natural lubrication and anti-inflammatory properties to create the ideal environment to proliferate and remodel damaged tissue.

In clinical application, Anu RHEO™ amniotic fluid matrix products are best utilized for minimally invasive treatment of damaged or inadequate tissue with its anti-inflammatory, anti-microbial and regenerative properties. Damaged tissue can be repaired at a more efficient rate when the extracellular matrix that Anu RHEO™ provides places ease on the infiltration, attachment, and proliferation of cells. Anu RHEO™ also supplies surgical and wound sites with an anti-microbial and anti-inflammatory environment,
effectively promoting tissue regeneration.

Anu RHEO™ is processed from donated human tissue from full term deliveries with adherence to American Association of Tissue Banks (AATB) standards. It is regulated as a human cell, tissue, or cellular or tissue-based product (HCT/P) under 21 CFR Part 1271 and Section 361 of the Public Health Service Administration.

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